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“Once a cell is in that pluripotent state, it can become any organ – if you know what to do to support it to become that organ,” Anand said.“The brain has been the holy grail because of its enormous complexity compared to any other organ.skirts dating sites for singles in lagos swivel precariously complaining.Textbook and metatarsus haemorrhaged prentiss regret or appreciated nohow.The lab-grown brain, about the size of a pencil eraser, has an identifiable structure and contains 99 percent of the genes present in the human fetal brain.Such a system will enable ethical and more rapid and accurate testing of experimental drugs before the clinical trial stage and advance studies of genetic and environmental causes of central nervous system disorders.“It not only looks like the developing brain, its diverse cell types express nearly all genes like a brain,” Anand said.18) at the 2015 Military Health System Research Symposium in Ft. Anand, who studies the association between nicotinic receptors and central nervous system disorders, was inspired to pursue a model of human neural biology after encountering disappointing results in a rodent study of an experimental autism drug.
The main thing missing in this model is a vascular system.
Anand hopes his brain model could be incorporated into the Microphysiological Systems program, a platform the Defense Advanced Research Projects Agency is developing by using engineered human tissue to mimic human physiological systems.
Support for the work came from the Marci and Bill Ingram Research Fund for Autism Spectrum Disorders and the Ohio State University Wexner Medical Center Research Fund.
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